Hamish Watson and Charlie Shiel are among nine players leaving Edinburgh at the end of the season.
Watson, who has made 181 appearances, is currently on a short-term loan with Leicester, while scrum-half Shiel has played 93 times.
Some of the other departing players, such as Lions-bound Boan Venter, had previously confirmed their exits.
Completing the list of departures are James Lang, Ben Healy, Sam Skinner, Angus Williams, Ross McCann and Mikey Jones.
“Every one of them has given their all for the jersey, and I want to express my sincere gratitude for the commitment and passion they’ve shown for Edinburgh,” said head coach Sean Everitt.
“We wish them nothing but the very best in the next stage of their careers.
“We obviously want to give a special mention to Hamish Watson – an all-time Edinburgh legend and one of the finest players ever to represent this club.
“We hope he gets back to full fitness soon and has every opportunity to challenge for silverware with Leicester Tigers at the end of the season. He deserves that.”
Venter and Shiel could make farewell appearances off the bench when Edinburgh host Dragons on Friday in their final URC fixture of the season.
